Amphibolite trails
Amphibolites, amphibolites, amphibolism - a group of metabolic pathways that function both in anabolism and catabolism. Amphibolites are, for example, glycolysis, Krebs cycle, gluconeogenesis, hexose monophosphate pathway. The compounds formed in this type of transformation can be decomposed to produce energy or serve as carbon skeletons for subsequent synthesis.
The term was proposed by B.D. Davis in 1961, recognizing that classification solely for catabolism and anabolism is not sufficient.
The performance of differentiated functions by metabolic pathways requires precise regulation at the molecular level. This is done by altering the activity of enzymes catalyzing key reactions. These enzymes also act as a receptor for the signal, which is a ligand. Another form of regulation of amphibolites is the change in the amount of individual enzymes through their de novo synthesis. As a result of the evolution of one metabolic pathway, two separate reaction groups may be formed. Calvina is used in chloroplasts to provide the synthesis of sugars from CO2. In the cytosol there are reverse reactions capable of gaining energy called the pentose phosphate oxidative pathway. The spinach enzyme D-ribulose-5-phosphate (R5P3E) (EC 5.1.3.1) is an amphibole enzyme found exclusively in chloroplasts.
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